Asetilsistein
 | Artikel ko maagiah informasi dasa tantang topik kasihatan. Informasi dalam artikel ko buliah digunoan anyo untuak panjalehan ilmiah, bukan untuak diagnosis diri dan indak dapek manggantian diagnosis medis. Paratian: Informasi dalam artikel ko bukanlah resep atau nasihaik medis. Wikipedia bukan pangganti dotor. Kok Sanak paralu bantuan atau ka barubek bakonsultasilah jo tanago kasihatan profesional. |
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| Data klinis | |
|---|---|
| Palafalan | /əˌsiːtəlˈsɪstiiːn/ and similar (/əˌsɛtəlʔ,_ˌæsᵻtəlʔ,_ʔtiːn/) |
| Namo dagang | Acetadote, Fluimucil, Mucomyst, lainnyo |
| Namo lain | N-acetylcysteine; N-acetyl-L-cysteine; NALC; NAC |
| AHFS/Drugs.com | Monograph |
| Lisensi data |
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| Kategori pado kahamilan | |
| Rute masuak ubek | lewat muluik, injeksi, inhalasi |
| Kode ATC | |
| Status legal | |
| Status legal | |
| Farmakokinetik data | |
| Bioavailabilitas | 10% (Oral)[2] |
| Ikatan protein | 50 hinggo 83%[1] |
| Metabolisme | Hati[1] |
| Eliminasi wakatu paruah | 5.6 jam[3] |
| Ekskresi | Renal (30%),[1] faecal (3%) |
| Pangenal | |
(2R)-2-acetamido-3-sulfanylpropanoic acid[4]
| |
| Nomor CAS | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.009.545  |
| Data kimia jo fisika | |
| Formula | C5H9NO3S |
| Molar mass | 163.195 g·mol−1 |
| 3D model (JSmol) | |
| Specific rotation | +5° (c = 3% in water)[5] |
| Melting point | 109 to 110 °C (228 to 230 °F) [5] |
C/C(=N/[C@@H](CS)C(=O)O)/O | |
InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1  Key:PWKSKIMOESPYIA-BYPYZUCNSA-N | |
| (verify) | |
Acetylcysteine, tanamo juo jo N-acetylcysteine, adolah ubek nan digunoan untuak maubeki overdosis parasetamol, jo malonggarkan lendir kental pado individu jo fibrosis kistik atau panyakik paru obstruktif kronis. Ubek ko dapek diambiak sacaro intravena, lewat muluik, atau dihiruik sabagai kabuik.
Referensi
[suntiang | suntiang sumber]- ↑ a b c "Acetylcysteine". The American Society of Health-System Pharmacists. Diarsipkan dari versi asli tanggal 23 September 2015.
- ↑ Stockley, Robert A. (2008). Chronic Obstructive Pulmonary Disease a Practical Guide to Management.. Chichester: John Wiley & Sons. p. 750. ISBN 9780470755280. https://books.google.com/books?id=y9li1geShyYC&pg=PA750.
- ↑ "ACETADOTE (acetylcysteine) injection, solution [Cumberland Pharmaceuticals Inc.]". DailyMed. Cumberland Pharmaceuticals Inc. June 2013. Diarsipkan dari versi asli tanggal 13 January 2014. Diakses tanggal 8 November 2013.
- ↑ "L-Cysteine, N-acetyl- - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. Identification. Diarsipkan dari versi asli tanggal 12 January 2014.
- ↑ a b "N-ACETYL-L-CYSTEINE Product Information" (PDF). Sigma. Sigma-aldrich. Diarsipkan dari versi asli (PDF) tanggal 11 June 2014.