Valgansiklovir

Valgansiklovir
Data klinis
Namo dagang	Valcyte
AHFS/Drugs.com	Monograph
MedlinePlus	a605021
Kategori pado kahamilan	US: C (Risk not ruled out) ;
Rute; masuak ubek	Lewat muluik (oral)
Kode ATC	J05AB14 (WHO) ;
Status legal
Status legal	UK: POM (Jo resep dotor) ; US: ℞-only ;
Farmakokinetik data
Bioavailabilitas	60%
Ikatan protein	1–2%
Metabolisme	Dihidrolisis ke ganskilovir
Eliminasi wakatu paruah	4 jam
Ekskresi	Ginjal
Pangenal
	Namo IUPAC 2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl-(2S)-2-amino-3-methylbutanoate;
Nomor CAS	175865-60-8 ;
PubChem CID	135413535;
IUPHAR/BPS	4716;
DrugBank	DB01610 ;
ChemSpider	57721 ;
UNII	GCU97FKN3R;
ChEMBL	ChEMBL1201314 ;
NIAID ChemDB	032967;
CompTox Dashboard (EPA)	DTXSID8048288 ;
Data kimia jo fisika
Formula	C14H22N6O5
Molar mass	354.362 g/mol g·mol−1
3D model (JSmol)	Gambar interaktif;
	SMILES O=C(OCC(OCn1c2N\C(=N/C(=O)c2nc1)N)CO)[C@@H](N)C(C)C;
	InChI InChI=1S/C14H22N6O5/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22)/t8?,9-/m0/s1 ; Key:WPVFJKSGQUFQAP-GKAPJAKFSA-N ;
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Valgansiklovir atau namo nan dipasarkan valcyte adolah ubek antivirus nan digunoan dalam pananganan jo pancagahan panyakik nan disababkan dek sitomegalovirus pado pandarito panyakik AIDS atau panarimo donor organ.^[2]^[3] Ubek ko tamasuak ka dalam ciek dari banyak ubek nan ado di Daftar Ubek Esensial Organisasi Kasihatan Dunia.^[4]

Rujuakan

↑ "Valganciclovir Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 27 October 2020. Pemeliharaan CS1: Url tak layak (link)
↑ "VALGANSIKLOVIR (PRO-DRUG DARI GANSIKLOVIR)" (dalam bahasa Indonesia). Pusat Informasi Obat Nasional (Badan Pengawas Obat dan Makanan). Diarsipkan dari versi asli tanggal 16 February 2019. Diakses tanggal 9 April 2020.
↑ "VALCYTE TABLET 450 MG" (dalam bahasa Indonesia). Halodoc. Diakses tanggal 9 April 2020. ^{[pranala nonaktif permanen]}
↑ World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 6 Juni 2019. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.

[AHFS2016-1] "Valganciclovir Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 27 October 2020. Pemeliharaan CS1: Url tak layak (link)

[refindo1-2] "VALGANSIKLOVIR (PRO-DRUG DARI GANSIKLOVIR)" (dalam bahasa Indonesia). Pusat Informasi Obat Nasional (Badan Pengawas Obat dan Makanan). Diarsipkan dari versi asli tanggal 16 February 2019. Diakses tanggal 9 April 2020.

[refindo2-3] "VALCYTE TABLET 450 MG" (dalam bahasa Indonesia). Halodoc. Diakses tanggal 9 April 2020. ^{[pranala nonaktif permanen]}

[WHO21st-4] World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 6 Juni 2019. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.

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